ea0029oc15.4 | Thyroid Basic | ICEECE2012
Marelli F.
, Gentilini D.
, Weber G.
, Vigone M.
, Radetti G.
, Persani L.
Introduction: Epidemiological data indicate that children born prematurely have a risk 35 fold higher of congenital hypothyroidism (CH). In addition premature infants born small for gestational age (SGA) have a risk of 12% higher to develop IC compared to prematures with appropriate development (AGA). The mechanisms that justify the increased risk of IC are still unknown. Some studies report a pattern of aberrant methylation associated with prematurity, intrauterine feta...